Recent Publications


Stephen T. Ferguson, Anandasankar Ray, Laurence J. Zwiebel, 2020,Olfactory genomics of eusociality within the Hymenoptera. Insect Pheromone Biochemistry and Molecular Biology. (Editors Blomquist-Vogt) In press

Keran Ye, Gustavo J. Correa, Tom Guda, Hanzhe Teng, Anandasankar Ray, Konstantinos Karydis, 2020, Development and Testing of a Novel Automated Insect Capture Module for Sample Collection and Transfer. arXiv:2008.12920. [Accepted to IEEE International Conference on Automation Science and Engineering (CASE) 2020]

Kowalewski, Joel and Ray, Anandasankar, 2020, Predicting novel drugs for SARS-CoV-2 using machine learning from a >10 million chemical space.Heliyon 6, 8, E04639. DOI:

Kowalewski, Joel and Ray, Anandasankar, 2020, Predicting Human Olfactory Perception from Activities of Odorant Receptors. iScience 23, 101361. DOI:

Kumar, Arun; Tauxe, Genevieve M; Perry, Sarah; Scott, Christi Ann; Dahanukar, Anupama; Ray, Anandasankar, 2020,Contributions of the Conserved Insect Carbon Dioxide Receptor Subunits to Odor Detection. Cell Reports 31, 107510.

Lisa Soyeon BaikCeazar NaveDavid D. AuTom GudaJoshua A. ChevezAnandasankar RayTodd C. Holmes. Circadian regulation of light-evoked attraction/avoidance in day- vs. night-biting mosquitoes
Current Biology 627588; DOI:


Iliano V. Coutinho-Abreu, Kavita Sharma, Liwang Cui, Guiyun Yan and Ray, A. Odorant ligands for the CO2 receptor in two Anopheles vectors of malaria. Scientific Reports. 9: 2549. DOI: 10.1038/s41598-019-39099-0

Reichert W, Ejercito J, Guda T, Dong X, Wu Q, Ray, A, Simon JE. Repellency Assessment of Nepeta cataria Essential Oils and Isolated Nepetalactones on Aedes aegypti. Scientific Reports. 9: 1524. PMID 30728370 DOI: 10.1038/s41598-018-36814-1 


MacWilliam D, Kowalewski J, Kumar A, Pontrello C and Ray A. (2018) Signaling Mode of the Broad-Spectrum Conserved CO2 Receptor Is One of the Important Determinants of Odor Valence in Drosophila. Neuron, DOI:

Ghaninia, M., Berger, S.L., Reinberg, D., Zwiebel, L.J., Ray, A. and Liebig J. (2018) Antennal Olfactory Physiology and Behavior of Males of the Ponerine Ant Harpegnathos saltator.J Chem Ecol, 44: 999.


Pask GM, Slone JD, Millar JG, Das P, Moreira JA, Zhou X, Bello J, Berger SL, Bonasio R, Desplan C, Reinberg D, Liebig J, Zwiebel LJ and Ray A. (2017) Specialized Odorant Receptors in social insects that detect cuticular hydrocarbon cues and candidate pheromones. Nature Communications, 8, Article number: 297 (2017) doi:10.1038/s41467-017-00099-1

Jesse D. Slone, Gregory M. Pask, Stephen T. Ferguson, Jocelyn G. Millar, Shelley L. Berger, Danny Reinberg, Jürgen Liebig, Anandasankar Ray and Laurence J. Zwiebel. (2017) Functional characterization of odorant receptors in the ponerine ant, Harpegnathos saltator. Proceedings of the National Academy of Sciences USA, doi: 10.1073/pnas.1704647114. Epub 2017 July 10.

Majid Ghaninia, Kevin Haight, Shelley L. Berger, Danny Reinberg, Laurence J. Zwiebel, Anandasankar Ray & Jürgen Liebig (2017) Chemosensory sensitivity reflects reproductive status in the ant Harpegnathos saltator. Scientific Reports 7, Article number: 3732 doi:10.1038/s41598-017-03964-7

Perry S, Beril K, Dickman D and Ray A. (2017) The Role of Histone Deacetylase 6 in Synaptic Plasticity and Memory. CELL Reports 18(6):1337-1345.


Boyle SB*, McInally S*, Tharadra S & Ray, A (2016) Short-term memory trace mediated by termination kinetics of olfactory receptor. Scientific Reports 6, Article number: 19863. doi:10.1038/srep19863

Simola DF, Graham RJ,, Brady CM, Enzmann BL, Desplan C, Ray, A, Zwiebel LJ, Bonasio R, Reinberg D, Liebig J, Berger SL. (2016) Epigenetic (re)programming of caste-specific behavior in the ant Camponotus floridanus. Science. 351(6268):aac6633. doi: 10.1126/science.aac6633

Pask, G. and Ray, A. (2016) Insect Olfactory Receptors: An Interface Between Chemistry and Biology in Chemosensory Transduction: Detection of Odor, Taste and Other Chemostimuli. Edited by: Zufall and Munger. Elsevier. I2016:101–122. ISBN: 9780128016947.

Boyle, SM, Guda, T., Pham, C., Dahanukar, A. and Ray, A. (2016) Natural DEET substitutes that are strong olfactory repellents of mosquitoes and flies. bioRxiv 060178; doi:

Clark JT, and Ray A. (2016) Olfactory Mechanisms for Discovery of Odorants to Reduce Insect-Host Contact. Journal of Chemical Ecology 42(9):919-930. (Review)


Sharma, K., Enzemann, B.L., Schmidt, Y., Moore, D., Jones, G.R., Parker, J., Berger, S.L., Reinberg, D., Zwiebel, L.J., Breit, B., Liebig, J. and Ray, A. (2015) Cuticular Hydrocarbon Pheromones for Social Behavior and their Coding in the Ant Antenna. Cell Reports. DOI:

Zhou, X., Rokas, A., Berger, S.L., Reinberg, D., Bonasio, R., Liebig, J., Ray, A. and Zwiebel, L.J. (2015) Chemoreceptor evolution in Hymenoptera and its implication for the evolution of eusociality. Genome Biology and Evolution. doi: 10.1093/gbe/evv149.

Ray, A. (2015) Reception of odors and repellents in mosquitoes. Current Opinion in Neurobiology 34: 158-164.

Pham, C.K. and Ray, A. (2015) Conservation of Olfactory Avoidance in Drosophila Species and Identification of Repellents for Drosophila suzukii. Scientific Reports. 5: 11527 doi:10.1038/srep11527.

Guda, T., Kain, P., Sharma, K.R., Pham, C.K. and Ray, A. (2015) Repellent compound with larger protective zone than DEET identified through activity-screening of Ir40a neurons, does not require Or function. bioRxiv. doi:


Clark JT and Ray A. (2014) The taste of togetherness. eLife. 2014;3:e05490. doi:10.7554/eLife.05490.

Coutinho-Abreu, Forster, L., Guda, T. and Ray A. (2014). Odorants for Surveillance and Control of the Asian Citrus Psyllid (Diaphorina citri) . PLoS ONE 9(10): e109236. doi:10.1371/journal.pone.0109236

Ray A.*, van Naters WG and Carlson JR (2014) Molecular determinants of odorant receptor function in insects. J. Biosci. 39 1–9 DOI 10.1007/s12038-014-9447-7

Coutinho-Abreu, I.V., McInally, S., Forster, L., Luck, R. and Ray A. (2014). Odor Coding in a Disease Transmitting Herbivorous Insect, the Asian Citrus Psyllid. Chemical Senses doi:10.1093/chemse/bju023

Liu Y-C, Pearce MW, Honda T, Johnson TK, Charlu S,Sharm KR, Imad M, Burke RE, Zinsmaier KE, Ray A, Dahanukar A, de Bruyne M and Warr CG (2014) The Drosophila melanogaster Phospholipid Flippase dATP8B Is Required for Odorant Receptor Function. PLoS Genet 10(3): e1004209. doi:10.1371/journal.pgen.1004209

Lacey ES, Ray A and Cardé R (2014) Close encounters: contributions of carbon dioxide and human skin odour to finding and landing on a host in Aedes aegypti. Physiological Entomology DOI: 10.1111/phen.12048.


Tauxe G*, MacWilliam D*, Boyle SM*, Guda T, and Ray A (2013) Targeting a Dual Detector of Skin and CO2 to Modify Mosquito Host Seeking. CELL 155, Issue 6, 1365-1379.

[Featured article: FREE, Paper Clip]

Boyle SM, McInally S and Ray A (2013) Expanding the olfactory code by in silico decoding of odor-receptor chemical space. eLife 2013; 2:e01120

Tharadra SK, Medina A, Ray A (2013) Advantage of the Highly Restricted Odorant Receptor Expression Pattern in Chemosensory Neurons of Drosophila. PLoS ONE 8(6): e66173. doi:10.1371/journal.pone.0066173


Sim, C. K*, Perry, S*, Tharadra, S. K., Lipsick, J. S., and Ray, A (2012). Epigenetic regulation of olfactory receptor gene expression by the Myb–MuvB/dREAM complex. Genes and Development, 26,  2483-2498.

[Genes & Dev. Cover story, Nov 15 issue ]

X Zhou*, J D Slone*, A Rokas, S Berger, J Liebig, A Ray,D Reinberg, and L J. Zwiebel (2012). Phylogenetic and transcriptomic analysis of chemosensory receptors in a pair of divergent ant species reveals caste-specific signatures of odor coding. PLoS Genetics 8(8): e1002930.


Turner SL*, Li N*, Guda T, Githure J, Cardé R, Ray A.( 2011) Ultra-prolonged activation of CO2-sensing neurons disorients mosquitoes. Nature 474, 87–91.

[Nature Cover story, June 2 issue ][ Malaria: mosquitoes Bamboozled, Mark Stopfer, News and Views ]

Dahanukar, A., Ray, A. (2011) Courtship, Aggression and Avoidance; Pheromones, Receptors and Neurons for Social Behaviors in Drosophila. Fly 1;5(1):58-63.

Tom, W., deBruyne, M., Haehnel, M., Carlson, J.R., Ray, A. (2011) Disruption of Olfactory Receptor Neuron Patterning in Scutoid mutant Drosophila. Molecular and Cellular Neuroscience. 46(1):252-61. Epub 2010 Sep 26.


Turner SL and Ray A. (2009) Modification of CO2 avoidance behaviour in Drosophila by inhibitory odorants. Nature doi:10.1038/nature08295.

Fuss SH. and Ray A. (2009) Mechanisms of odorant receptor gene choice in Drosophila and vertebrates. Molecular and Cellular Neuroscience 41(2009) 101-112 (PDF).


Tichy A., Ray A., and Carlson JR (2008) A new Drosophila POU gene, pdm3, acts in odor receptor expression and axon targeting of olfactory neurons. Journal of Neuroscience July 9, 28, 7121-7129.

Ray A., van der Goes van Naters, and Carlson JR (2008) A Regulatory Code for Neuron-Specific Odor Receptor Expression. PLoS Biology 6(5): e125 doi:10.1371/journal.pbio.0060125

[PLos Biol. Cover story]


Ray, A., van der Goes van Naters, W., Shiraiwa, T., and Carlson, J. R. (2007). Mechanisms of odor receptor gene choice in Drosophila. Neuron 53, 353-369.